STAMBPL1 Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Belongs to the peptidase M67C family. Ubiquitously expressed. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; EC 3.1.2.15; EC 3.4.19.-; Protease
Chromosomal Location of Human Ortholog: 10q23.31
Cellular Component:  cytosol
Molecular Function:  Lys63-specific deubiquitinase activity; metal ion binding; metallopeptidase activity; protein binding
Biological Process:  protein deubiquitination
Reference #:  Q96FJ0 (UniProtKB)
Alt. Names/Synonyms: ALMalpha; AMSH-FP; AMSH-like protease; AMSH-LP; AMSHLP; associated molecule with the SH3 domain of STAM (AMSH) - Family Protein; associated molecule with the SH3 domain of STAM (AMSH) like protein; bA399O19.2; FLJ31524; KIAA1373; STALP; STAM binding protein like 1; STAM binding protein-like 1; STAM-binding protein-like 1; STAMBPL1
Gene Symbols: STAMBPL1
Molecular weight: 49,783 Da
Basal Isoelectric point: 6.79  Predict pI for various phosphorylation states
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STAMBPL1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene