CP110 Necessary for centrosome duplication at different stages of procentriole formation. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 7|7 F2
Cellular Component:  cell projection; centriole; centrosome; cilium; cytoplasm; cytoskeleton; microtubule organizing center; protein-containing complex
Molecular Function:  protein binding
Biological Process:  cell projection organization; centriole replication; centrosome duplication; ciliary basal body organization; negative regulation of cilium assembly; positive regulation of cilium assembly; regulation of cytokinesis
Reference #:  Q7TSH4 (UniProtKB)
Alt. Names/Synonyms: 6330503K22Rik; AA415922; AI427129; AW557948; CE110; Centriolar coiled-coil protein of 110 kDa; Centrosomal protein of 110 kDa; Cep110; Cp110; Kiaa0419; OTTMUSP00000031985; RIKEN cDNA 6330503K22 gene
Gene Symbols: CCP110
Molecular weight: 111,139 Da
Basal Isoelectric point: 9.01  Predict pI for various phosphorylation states
Select Structure to View Below

CP110

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene