DUSP14 Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.16; EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity
Chromosomal Location of Human Ortholog: 11 C|11 51.29 cM
Cellular Component:  cytoplasm; nucleus
Molecular Function:  hydrolase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphatase activity; phosphoprotein phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity
Biological Process:  dephosphorylation; protein dephosphorylation
Reference #:  Q9JLY7 (UniProtKB)
Alt. Names/Synonyms: 1110014C10Rik; 2310042C07Rik; D11Ertd395; D11Ertd395e; dual specificity phosphatase 14; Dual specificity protein phosphatase 14; DUS14; Dusp14; MAP kinase phosphatase 6; MAP kinase phsophatase 6; Mitogen-activated protein kinase phosphatase 6; Mkp; Mkp-1 like protein tyrosine phosphatase; MKP-6; MKP-L; Mkp6; OTTMUSP00000000916; OTTMUSP00000000917; OTTMUSP00000000919
Gene Symbols: Dusp14
Molecular weight: 22,311 Da
Basal Isoelectric point: 9.48  Predict pI for various phosphorylation states
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DUSP14

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene