BTN3A3
Plays a role in T-cell responses in the adaptive immune response. Belongs to the immunoglobulin superfamily. BTN/MOG family. Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Cell surface; Membrane protein, integral |
Chromosomal Location of human Ortholog: 6p22.2 |
Cellular Component:
external side of plasma membrane; plasma membrane
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Molecular Function:
signaling receptor binding
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Biological Process:
regulation of cytokine production; T cell mediated immunity; T cell receptor signaling pathway
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Reference #:
O00478
(UniProtKB)
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Alt. Names/Synonyms: BT3A3; BTF3; BTN3.3; BTN3A3; butyrophilin 3; Butyrophilin subfamily 3 member A3; butyrophilin, subfamily 3, member A3
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Gene Symbols: BTN3A3
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Molecular weight:
65,002 Da
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Basal Isoelectric point:
5.37
Predict pI for various phosphorylation states
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