PSRC2 Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 12q21.1
Cellular Component:  exosome (RNase complex); nucleus
Molecular Function:  metal ion binding; protein binding
Biological Process:  RNA processing
Reference #:  O60293 (UniProtKB)
Alt. Names/Synonyms: CCDC131; coiled-coil domain containing 131; Coiled-coil domain-containing protein 131; CSRC2; DKFZp686A0722; KIAA0546; MGC23401; MGC90200; proline/serine-rich coiled-coil 2; Proline/serine-rich coiled-coil protein 2; PSRC2; ZC3H1; ZFC3H1; Zinc finger C3H1 domain-containing protein; zinc finger C3H1-type containing; zinc finger, C3H1-type containing
Gene Symbols: ZFC3H1
Molecular weight: 226,356 Da
Basal Isoelectric point: 8.39  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene