DUSP5 Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.16; EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity
Chromosomal Location of Human Ortholog: 10q25.2
Cellular Component:  nucleoplasm
Molecular Function:  phosphatase activity; protein binding; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity
Biological Process:  activation of MAPK activity; dephosphorylation; MAPK cascade; peptidyl-threonine dephosphorylation; peptidyl-tyrosine dephosphorylation; protein dephosphorylation
Reference #:  Q16690 (UniProtKB)
Alt. Names/Synonyms: dual specificity phosphatase 5; Dual specificity protein phosphatase 5; Dual specificity protein phosphatase hVH3; DUS5; DUSP; DUSP5; HVH3; serine/threonine specific protein phosphatase; VH1-like phosphatase 3; VH3
Gene Symbols: DUSP5
Molecular weight: 42,047 Da
Basal Isoelectric point: 8.69  Predict pI for various phosphorylation states
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DUSP5

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene