SOGA2 Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells. Belongs to the SOGA family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 18p11.22
Cellular Component:  apical plasma membrane; apicolateral plasma membrane; cytoplasm; cytoskeleton; extracellular space; lateral plasma membrane; microtubule bundle; midbody; spindle pole
Molecular Function:  microtubule binding; protein homodimerization activity
Biological Process:  establishment or maintenance of epithelial cell apical/basal polarity; microtubule bundle formation; positive regulation of microtubule motor activity; positive regulation of protein targeting to membrane; regulation of autophagy
Reference #:  Q9Y4B5 (UniProtKB)
Alt. Names/Synonyms: CCDC165; Coiled-coil domain-containing protein 165; KIAA0802; LOC23255; Microtubule cross-linking factor 1; microtubule crosslinking factor 1; MTCL1; PAR-1-interacting protein; SOGA family member 2; SOGA2
Gene Symbols: MTCL1
Molecular weight: 209,526 Da
Basal Isoelectric point: 6.03  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  CCLE  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein