UBE3B E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 6.3.2.-; EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 12q24.11
Cellular Component:  cytoplasm
Biological Process:  protein ubiquitination
Disease: Kaufman Oculocerebrofacial Syndrome
Reference #:  Q7Z3V4 (UniProtKB)
Alt. Names/Synonyms: DKFZp586K2123; DKFZp686A1051; FLJ45294; MGC131858; MGC78388; UBE3B; ubiquitin protein ligase E3B; Ubiquitin-protein ligase E3B
Gene Symbols: UBE3B
Molecular weight: 123,098 Da
Basal Isoelectric point: 8.51  Predict pI for various phosphorylation states
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UBE3B

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein