RRH May play a role in rpe physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds. Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. Found only in the eye, where it is localized to the retinal pigment epithelium (RPE). In the RPE, it is localized to the microvilli that surround the photoreceptor outer segments. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 4q25
Cellular Component: 
Molecular Function:  G protein-coupled receptor activity
Biological Process:  detection of visible light; protein-chromophore linkage; visual perception
Reference #:  O14718 (UniProtKB)
Alt. Names/Synonyms: opsx; peropsin; retinal pigment epithelium-derived rhodopsin; retinal pigment epithelium-derived rhodopsin homolog; rrh; Visual pigment-like receptor peropsin
Gene Symbols: RRH
Molecular weight: 37,423 Da
Basal Isoelectric point: 8.78  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein