NUP155 Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport. Belongs to the non-repetitive/WGA-negative nucleoporin family. Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Nucleoporin
Chromosomal Location of human Ortholog: 5p13.2
Cellular Component:  cytosol; nuclear envelope; nuclear membrane; nuclear pore; nuclear pore inner ring
Molecular Function:  protein binding; structural constituent of nuclear pore
Biological Process:  atrial cardiac muscle cell action potential; miRNA processing; mRNA export from nucleus; nuclear envelope organization; nucleocytoplasmic transport; protein import into nucleus; protein localization to nuclear inner membrane; RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
Disease: Atrial Fibrillation, Familial, 15
Reference #:  O75694 (UniProtKB)
Alt. Names/Synonyms: 155 kDa nucleoporin; ATFB15; KIAA0791; N155; NU155; Nuclear pore complex protein Nup155; nucleoporin 155; nucleoporin 155kD; nucleoporin 155kDa; Nucleoporin Nup155; NUP155
Gene Symbols: NUP155
Molecular weight: 155,199 Da
Basal Isoelectric point: 5.78  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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