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COX3
Subunits I, II and III form the functional core of the enzyme complex. Belongs to the cytochrome c oxidase subunit 3 family. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Oxidoreductase |
| Chromosomal Location of human Ortholog: - |
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Cellular Component:
mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV
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Molecular Function:
cytochrome-c oxidase activity; protein binding
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Biological Process:
cellular respiration; mitochondrial electron transport, cytochrome c to oxygen; proton transmembrane transport; respiratory chain complex IV assembly
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Disease: Leber Optic Atrophy; Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-like Episodes
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Reference #:
P00414
(UniProtKB)
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Alt. Names/Synonyms: COIII; COX3; COXIII; cytochrome c oxidase III; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3; cytochrome c oxidase subunit III; mitochondrially encoded cytochrome c oxidase III; MT-CO3; MTCO3
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Gene Symbols: MT-CO3
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Molecular weight:
29,951 Da
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Basal Isoelectric point:
6.78
Predict pI for various phosphorylation states
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