hnRNP H1 This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). Expressed ubiquitously. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 10q22
Cellular Component:  catalytic step 2 spliceosome; cytosol; nucleoplasm; nucleus; postsynaptic density; spliceosomal complex
Molecular Function:  enzyme binding; RNA binding
Biological Process:  cellular response to interleukin-7; cellular response to peptide; mRNA processing; regulation of RNA splicing; RNA processing; RNA splicing
Reference #:  Q8VHV7 (UniProtKB)
Alt. Names/Synonyms: Heterogeneous nuclear ribonucleoprotein H; Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; heterogeneous nuclear ribonucleoprotein H1; HNRH1; hnRNP H; hnRNP H1; Hnrnph1; Hnrph; Hnrph1; MGC124573; Ratsg1
Gene Symbols: Hnrnph1
Molecular weight: 49,188 Da
Basal Isoelectric point: 5.7  Predict pI for various phosphorylation states
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hnRNP H1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene