|
PTPRA
Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine |
| Chromosomal Location of Human Ortholog: 20p13 |
|
Cellular Component:
integral component of plasma membrane; integral component of synaptic membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse
|
|
Molecular Function:
protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity
|
|
Biological Process:
axon guidance; insulin receptor signaling pathway; MAPK cascade; modulation of chemical synaptic transmission; peptidyl-tyrosine dephosphorylation
|
|
Reference #:
P18433
(UniProtKB)
|
|
Alt. Names/Synonyms: HEPTP; HLPR; HPTPA; HPTPalpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); LRP; protein tyrosine phosphatase, receptor type, A; protein tyrosine phosphatase, receptor type, alpha polypeptide; Protein-tyrosine phosphatase alpha; PTPase-alpha; PTPLCA-related phosphatase; PTPRL2; R-PTP-alpha; Receptor-type tyrosine-protein phosphatase alpha; RPTPA; tyrosine phosphatase alpha
|
|
Gene Symbols: PTPRA
|
|
Molecular weight:
90,600 Da
|
|
Basal Isoelectric point:
6.26
Predict pI for various phosphorylation states
|
