PTPRA Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine
Chromosomal Location of Human Ortholog: 20p13
Cellular Component:  integral component of plasma membrane; integral component of synaptic membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse
Molecular Function:  protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity
Biological Process:  axon guidance; insulin receptor signaling pathway; MAPK cascade; modulation of chemical synaptic transmission; peptidyl-tyrosine dephosphorylation
Reference #:  P18433 (UniProtKB)
Alt. Names/Synonyms: HEPTP; HLPR; HPTPA; HPTPalpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); LRP; protein tyrosine phosphatase receptor type A; protein tyrosine phosphatase, receptor type, A; protein tyrosine phosphatase, receptor type, alpha polypeptide; Protein-tyrosine phosphatase alpha; PTPA; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; R-PTP-alpha; Receptor-type tyrosine-protein phosphatase alpha; RPTPA; tyrosine phosphatase alpha
Gene Symbols: PTPRA
Molecular weight: 90,600 Da
Basal Isoelectric point: 6.26  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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