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PTPRA
Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine |
| Chromosomal Location of Human Ortholog: 20p13 |
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Cellular Component:
integral component of plasma membrane; integral component of synaptic membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse
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Molecular Function:
protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity
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Biological Process:
axon guidance; insulin receptor signaling pathway; MAPK cascade; modulation of chemical synaptic transmission; peptidyl-tyrosine dephosphorylation
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Reference #:
P18433
(UniProtKB)
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Alt. Names/Synonyms: HEPTP; HLPR; HPTPA; HPTPalpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); LRP; protein tyrosine phosphatase receptor type A; protein tyrosine phosphatase, receptor type, A; protein tyrosine phosphatase, receptor type, alpha polypeptide; Protein-tyrosine phosphatase alpha; PTPA; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; R-PTP-alpha; Receptor-type tyrosine-protein phosphatase alpha; RPTPA; tyrosine phosphatase alpha
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Gene Symbols: PTPRA
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Molecular weight:
90,600 Da
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Basal Isoelectric point:
6.26
Predict pI for various phosphorylation states
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