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coronin 2B
May play a role in the reorganization of neuronal actin structure. Belongs to the WD repeat coronin family. Expressed predominantly in brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Actin-binding; Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 9|9 B |
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Cellular Component:
cytoplasm; cytoskeleton; focal adhesion; stress fiber
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Molecular Function:
actin binding; actin filament binding; talin binding; vinculin binding
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Biological Process:
focal adhesion assembly; negative regulation of cell-substrate adhesion; negative regulation of establishment of protein localization; negative regulation of stress fiber assembly; positive regulation of establishment of protein localization; regulation of actin cytoskeleton organization; regulation of cellular response to stress; regulation of glomerular filtration
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Reference #:
Q8BH44
(UniProtKB)
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Alt. Names/Synonyms: CLIPINC; COR2B; Coro2b; coronin 2B; coronin, actin binding protein, 2B; Coronin-2B; E130012P22; E130012P22Rik; KIAA0925-like
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Gene Symbols: Coro2b
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Molecular weight:
54,936 Da
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Basal Isoelectric point:
8.53
Predict pI for various phosphorylation states
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