CAMK4 a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: CAMK group; CAMK1 family; EC; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 18p12
Cellular Component:  cytoplasm; fibrillar center; GABA-ergic synapse; glutamatergic synapse; nucleoplasm; nucleus; postsynapse
Molecular Function:  ATP binding; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; calmodulin-dependent protein kinase activity
Biological Process:  adaptive immune response; inflammatory response; intracellular signal transduction; long-term memory; myeloid dendritic cell differentiation; neuron-neuron synaptic transmission; nucleocytoplasmic transport; peptidyl-serine phosphorylation; positive regulation of protein export from nucleus; positive regulation of transcription, DNA-templated; postsynapse to nucleus signaling pathway; protein autophosphorylation; protein phosphorylation; signal transduction
Reference #:  P13234 (UniProtKB)
Alt. Names/Synonyms: calcium/calmodulin-dependent protein kinase IV; Calcium/calmodulin-dependent protein kinase type IV; Calmodulin-dependent protein kinase IV; Calspermin; CaM kinase-GR; CaMK IV; Camk4; Ccdpk; KCC4; RATCCDPK
Gene Symbols: Camk4
Molecular weight: 53,151 Da
Basal Isoelectric point: 4.85  Predict pI for various phosphorylation states
CST Pathways:  B Cell Receptor Signaling  |  ErbB/HER Signaling  |  GPCR Signaling to MAPKs  |  Microtubule Dynamics  |  T Cell Receptor Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene