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CAPNS1
Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Note: This description may include information from UniProtKB.
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| Protein type: Motility/polarity/chemotaxis; Protease |
| Chromosomal Location of human Ortholog: 19q13.12 |
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Cellular Component:
cytosol; membrane; plasma membrane
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Molecular Function:
calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; protein binding
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Biological Process:
cornification; extracellular matrix disassembly; positive regulation of cell proliferation; proteolysis; regulation of macroautophagy
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Reference #:
P04632
(UniProtKB)
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Alt. Names/Synonyms: 30K; calcium-activated neutral proteinase; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4, small subunit (30K); Calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; calpain, small subunit 1; CALPAIN4; CANP; CANP small subunit; CANPS; CAPN4; CAPNS; CAPNS1; CDPS; CPNS1; CSS1; epididymis secretory sperm binding protein
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Gene Symbols: CAPNS1
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Molecular weight:
28,316 Da
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Basal Isoelectric point:
5.05
Predict pI for various phosphorylation states
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CST Pathways:
Apoptosis Regulation
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