BLK a nonreceptor tyrosine kinase of the Src family. Expressed predominantly in B lymphocytes Note: This description may include information from UniProtKB.
Protein type: EC 2.7.10.2; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); Src family; TK group
Chromosomal Location of Human Ortholog: 14 D1|14 33.25 cM
Cellular Component:  extrinsic component of cytoplasmic side of plasma membrane; membrane; plasma membrane
Molecular Function:  ATP binding; kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; signaling receptor binding; transferase activity
Biological Process:  B cell receptor signaling pathway; cell differentiation; peptidyl-tyrosine autophosphorylation; peptidyl-tyrosine phosphorylation; phosphorylation; positive regulation of insulin secretion; protein phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
Reference #:  P16277 (UniProtKB)
Alt. Names/Synonyms: B lymphocyte kinase; B lymphoid kinase; Blk; p55-Blk; Tyrosine-protein kinase Blk
Gene Symbols: Blk
Molecular weight: 56,674 Da
Basal Isoelectric point: 6.7  Predict pI for various phosphorylation states
CST Pathways:  GPCR Signaling to MAPKs  |  Tyrosine Kinases & Substrates
Select Structure to View Below

BLK

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene