K6c Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009]
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component:  cytosol; intermediate filament; keratin filament
Molecular Function:  protein binding; structural molecule activity
Biological Process:  cornification; intermediate filament cytoskeleton organization; keratinization
Disease: Palmoplantar Keratoderma, Nonepidermolytic, Focal Or Diffuse
Reference #:  P48668 (UniProtKB)
Alt. Names/Synonyms: CK-6C; CK-6E; Cytokeratin-6C; Cytokeratin-6E; K2C6C; K6C; K6E; keratin 6C; keratin 6E; Keratin K6h; Keratin, type II cytoskeletal 6C; Keratin-6C; KRT6C; KRT6E; MGC102925; MGC163455; MGC163457; Type-II keratin Kb12
Gene Symbols: KRT6C
Molecular weight: 60,025 Da
Basal Isoelectric point: 8.09  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein