CD93 Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component:  cell surface; ficolin-1-rich granule membrane; integral component of membrane; plasma membrane; secretory granule membrane; specific granule membrane; tertiary granule membrane
Molecular Function:  calcium ion binding; carbohydrate binding; complement component C1q binding; protein binding; signaling receptor activity
Biological Process:  cell-cell adhesion; macrophage activation; neutrophil degranulation; phagocytosis; viral process
Reference #:  Q9NPY3 (UniProtKB)
Alt. Names/Synonyms: C1q receptor 1; C1q/MBL/SPA receptor; C1qR; C1qR(p); C1QR1; C1qRp; CD93; CD93 antigen; CD93 molecule; CDw93; Complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; Complement component C1q receptor; dJ737E23.1; ECSM3; Matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4
Gene Symbols: CD93
Molecular weight: 68,560 Da
Basal Isoelectric point: 5.27  Predict pI for various phosphorylation states
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CD93

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene