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ZCCHC12
Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression. Belongs to the ZCCHC12 family. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: Xq24 |
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Cellular Component:
nucleus
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Molecular Function:
nucleic acid binding; protein binding; zinc ion binding
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Reference #:
Q6PEW1
(UniProtKB)
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Alt. Names/Synonyms: 2810028A01Rik; FLJ16123; paraneoplastic Ma antigen family member 7A; PNMA7A; SIZN; SIZN1; Smad-interacting zinc finger protein 1; ZCCHC12; ZCH12; Zinc finger CCHC domain-containing protein 12; zinc finger CCHC-type containing 12; zinc finger, CCHC domain containing 12
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Gene Symbols: ZCCHC12
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Molecular weight:
45,369 Da
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Basal Isoelectric point:
5.87
Predict pI for various phosphorylation states
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