ZCCHC12 Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression. Belongs to the ZCCHC12 family. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: Xq24
Cellular Component:  nucleus
Molecular Function:  nucleic acid binding; protein binding; zinc ion binding
Reference #:  Q6PEW1 (UniProtKB)
Alt. Names/Synonyms: 2810028A01Rik; FLJ16123; paraneoplastic Ma antigen family member 7A; PNMA7A; SIZN; SIZN1; Smad-interacting zinc finger protein 1; ZCCHC12; ZCH12; Zinc finger CCHC domain-containing protein 12; zinc finger CCHC-type containing 12; zinc finger, CCHC domain containing 12
Gene Symbols: ZCCHC12
Molecular weight: 45,369 Da
Basal Isoelectric point: 5.87  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene