RSHL3 Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk which is attached to a subfiber of the outer doublet microtubule, and a bulbous head which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. Belongs to the flagellar radial spoke RSP4/6 family. Expressed in trachea, lungs, and testes. Very strong expression is detected in nasal brushings. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 6q22.1
Cellular Component:  axoneme; motile cilium; nucleolus; nucleoplasm; nucleus; radial spoke
Biological Process:  axoneme assembly; cilium movement
Disease: Ciliary Dyskinesia, Primary, 11
Reference #:  Q5TD94 (UniProtKB)
Alt. Names/Synonyms: CILD11; dJ412I7.1; FLJ37974; MGC126303; radial spoke head 4 homolog A (Chlamydomonas); Radial spoke head protein 4 homolog A; Radial spoke head-like protein 3; radial spokehead-like 3; RSH4A; RSHL3; RSPH4A; RSPH6B
Gene Symbols: RSPH4A
Molecular weight: 80,733 Da
Basal Isoelectric point: 4.38  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene