PPP2R5A
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B56 family. Widely expressed with the highest expression in heart and skeletal muscle. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit
Cellular Component: centrosome; chromosome, centromeric region; cytoplasm; cytosol; M band; nucleus; plasma membrane; protein phosphatase type 2A complex; Z disc
Molecular Function: kinase binding; phosphoprotein phosphatase activity; protein binding; protein phosphatase activator activity; protein phosphatase regulator activity
Biological Process: negative regulation of lipid kinase activity; negative regulation of protein localization to plasma membrane; positive regulation of protein dephosphorylation; protein dephosphorylation; signal transduction