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SPAG6
Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility. Highly expressed in testis. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cancer Testis Antigen (CTA); Cell development/differentiation |
| Chromosomal Location of rat Ortholog: 17q12.3 |
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Cellular Component:
acrosomal vesicle; axoneme; extracellular region; microtubule cytoskeleton; sperm principal piece
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Molecular Function:
microtubule binding
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Biological Process:
epithelial cilium movement involved in extracellular fluid movement; filopodium assembly; neuron projection extension; sperm axoneme assembly
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Reference #:
NP_001099595
(RefSeq)
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Alt. Names/Synonyms: CT141; Spag6; Spag6l; sperm associated antigen 6; sperm associated antigen 6-like
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Gene Symbols: Spag6l
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Molecular weight:
55,348 Da
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Basal Isoelectric point:
5.88
Predict pI for various phosphorylation states
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