AASDHPPT Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN. Belongs to the P-Pant transferase superfamily. AcpS family. Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - lysine biosynthesis; Amino Acid Metabolism - lysine degradation; EC 2.7.8.-; Transferase
Chromosomal Location of Human Ortholog: 11q22.3
Cellular Component:  cytosol
Molecular Function:  holo-[acyl-carrier-protein] synthase activity; magnesium ion binding; protein binding
Biological Process:  pantothenate metabolic process
Reference #:  Q9NRN7 (UniProtKB)
Alt. Names/Synonyms: 4'-phosphopantetheinyl transferase; AASD-PPT; AASDHPPT; ACPS; ADPPT; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; CGI-80; DKFZp566E2346; holo ACP synthase; holo-[acyl-carrier-protein] synthase; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; LYS2; LYS5; LYS5 ortholog
Gene Symbols: AASDHPPT
Molecular weight: 35,776 Da
Basal Isoelectric point: 6.35  Predict pI for various phosphorylation states
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AASDHPPT

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene