RRas a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Ras; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component:  plasma membrane
Molecular Function:  GDP binding; GTP binding; GTPase activity; protein binding; protein-containing complex binding
Biological Process:  face morphogenesis; leukocyte differentiation; negative regulation of cell migration; positive regulation of angiogenesis; Ras protein signal transduction; regulation of ERK1 and ERK2 cascade; regulation of protein kinase B signaling
Reference #:  P10301 (UniProtKB)
Alt. Names/Synonyms: Oncogene RRAS; p23; Ras-related protein R-Ras; related RAS viral (r-ras) oncogene homolog; RRAS
Gene Symbols: RRAS
Molecular weight: 23,480 Da
Basal Isoelectric point: 6.44  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  Angiogenesis  |  B Cell Receptor Signaling  |  ErbB/HER Signaling  |  ESC Pluripotency and Differentiation  |  GPCR Signaling to MAPKs  |  Growth And Differentiation Control by MAPKs  |  IL6 Signaling  |  Inhibition of Apoptosis  |  Insulin Receptor Signaling  |  NF-kB Signaling  |  SAPK/JNK Signaling Cascades  |  T Cell Receptor Signaling  |  TGF-ß Signaling  |  Warburg Effect
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene