NUP107 Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. Belongs to the nucleoporin Nup84/Nup107 family. Ubiquitously expressed in fetal and adult tissues. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Nucleoporin
Chromosomal Location of Human Ortholog: 12q15
Cellular Component:  condensed chromosome kinetochore; cytosol; host cell; nuclear envelope; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore outer ring
Molecular Function:  protein binding; structural constituent of nuclear pore
Biological Process:  female gonad development; intracellular transport of virus; mRNA export from nucleus; nephron development; nuclear pore complex assembly; protein sumoylation; regulation of cellular response to heat; regulation of gene silencing by miRNA; regulation of glycolytic process; tRNA export from nucleus; viral process; viral transcription
Disease: Galloway-mowat Syndrome 7; Nephrotic Syndrome, Type 11; Ovarian Dysgenesis 6
Reference #:  P57740 (UniProtKB)
Alt. Names/Synonyms: 107 kDa nucleoporin; GAMOS7; NPHS11; NU107; Nuclear pore complex protein Nup107; nucleoporin 107; nucleoporin 107kDa; Nucleoporin Nup107; NUP107; NUP84; ODG6
Gene Symbols: NUP107
Molecular weight: 106,374 Da
Basal Isoelectric point: 5.28  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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