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TLL2
Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.4.24.-; Protease; Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 10q24.1 |
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Cellular Component:
extracellular region
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Molecular Function:
calcium ion binding; metalloendopeptidase activity; zinc ion binding
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Biological Process:
cell differentiation; extracellular matrix disassembly; multicellular organism development; negative regulation of skeletal muscle tissue growth; proteolysis
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Reference #:
Q9Y6L7
(UniProtKB)
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Alt. Names/Synonyms: KIAA0932; MGC133312; MGC133313; TLL2; tolloid like 2; tolloid-like 2; Tolloid-like protein 2
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Gene Symbols: TLL2
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Molecular weight:
113,557 Da
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Basal Isoelectric point:
5.6
Predict pI for various phosphorylation states
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