PRMT3
Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: C2H2-type zinc finger protein; EC 2.1.1.-; Methyltransferase; Methyltransferase, protein arginine |
Chromosomal Location of human Ortholog: 11p15.1 |
Cellular Component:
cytoplasm; cytosol; nucleus
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Molecular Function:
metal ion binding; methyltransferase activity; protein binding; protein-arginine N-methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; ribosome binding
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Biological Process:
negative regulation of protein ubiquitination; negative regulation of retinoic acid biosynthetic process; peptidyl-arginine methylation; protein methylation
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Reference #:
O60678
(UniProtKB)
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Alt. Names/Synonyms: ANM3; heterogeneous nuclear ribonucleoprotein methyltransferase-like 3; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; HMT1 hnRNP methyltransferase-like 3; HRMT1L3; PRMT3; protein arginine methyltransferase 3; Protein arginine N-methyltransferase 3
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Gene Symbols: PRMT3
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Molecular weight:
59,903 Da
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Basal Isoelectric point:
5.18
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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