|
GPAA1
Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Endoplasmic reticulum; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Membrane protein, multi-pass |
| Chromosomal Location of mouse Ortholog: 15|15 D3 |
|
Cellular Component:
centrosome; cytosol; endoplasmic reticulum; GPI-anchor transamidase complex; membrane; mitochondrion; plasma membrane
|
|
Molecular Function:
GPI anchor binding; GPI-anchor transamidase activity
|
|
Biological Process:
attachment of GPI anchor to protein; GPI anchor biosynthetic process; protein-containing complex assembly
|
|
Reference #:
Q9WTK3
(UniProtKB)
|
|
Alt. Names/Synonyms: C80044; Gaa1; GAA1 protein homolog; Glycosylphosphatidylinositol anchor attachment 1 protein; Gpaa1; GPI anchor attachment protein 1; mGA; mGAA1
|
|
Gene Symbols: Gpaa1
|
|
Molecular weight:
67,949 Da
|
|
Basal Isoelectric point:
8.61
Predict pI for various phosphorylation states
|
