DCI
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Belongs to the enoyl-CoA hydratase/isomerase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: EC 5.3.3.8; Isomerase; Lipid Metabolism - fatty acid; Mitochondrial |
Chromosomal Location of mouse Ortholog: 17|17 A3.3 |
Cellular Component:
mitochondrion
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Molecular Function:
catalytic activity; delta(3)-delta(2)-enoyl-CoA isomerase activity; identical protein binding; intramolecular oxidoreductase activity, transposing C=C bonds; isomerase activity
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Biological Process:
fatty acid beta-oxidation; fatty acid metabolic process; lipid metabolic process
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Reference #:
P42125
(UniProtKB)
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Alt. Names/Synonyms: 3,2 trans-enoyl-Coenyme A isomerase; 3,2-trans-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase, mitochondrial; D3,D2-enoyl-CoA isomerase; D3D2; Dci; Delta(3),Delta(2)-enoyl-CoA isomerase; Dodecenoyl-CoA isomerase; dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase); eci; ECI1; Enoyl-CoA delta isomerase 1, mitochondrial; enoyl-Coenzyme A delta isomerase 1
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Gene Symbols: Eci1
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Molecular weight:
32,250 Da
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Basal Isoelectric point:
9.12
Predict pI for various phosphorylation states
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