MCUR1 Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU. Probably involved in the assembly of the membrane components of the uniporter complex (uniplex). Belongs to the CCDC90 family. Ubiquitously expressed. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial
Chromosomal Location of human Ortholog: 6p23
Cellular Component:  mitochondrial inner membrane; mitochondrion
Molecular Function:  protein binding
Biological Process:  calcium import into the mitochondrion; calcium ion import; mitochondrial calcium ion transmembrane transport; positive regulation of mitochondrial calcium ion concentration
Reference #:  Q96AQ8 (UniProtKB)
Alt. Names/Synonyms: C6orf79; CC90A; CCDC90A; coiled-coil domain containing 90A; Coiled-coil domain-containing protein 90A, mitochondrial; epididymis secretory sperm binding protein; FLJ20958; FMP32; MCU regulator 1; MCUR1; Mitochondrial calcium uniporter regulator 1
Gene Symbols: MCUR1
Molecular weight: 39,694 Da
Basal Isoelectric point: 9.67  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene