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MCUR1
Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU. Probably involved in the assembly of the membrane components of the uniporter complex (uniplex). Belongs to the CCDC90 family. Ubiquitously expressed. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial |
| Chromosomal Location of human Ortholog: 6p23 |
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Cellular Component:
mitochondrial inner membrane; mitochondrion
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Molecular Function:
protein binding
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Biological Process:
calcium import into the mitochondrion; calcium ion import; mitochondrial calcium ion transmembrane transport; positive regulation of mitochondrial calcium ion concentration
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Reference #:
Q96AQ8
(UniProtKB)
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Alt. Names/Synonyms: C6orf79; CC90A; CCDC90A; coiled-coil domain containing 90A; Coiled-coil domain-containing protein 90A, mitochondrial; epididymis secretory sperm binding protein; FLJ20958; FMP32; MCU regulator 1; MCUR1; Mitochondrial calcium uniporter regulator 1
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Gene Symbols: MCUR1
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Molecular weight:
39,694 Da
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Basal Isoelectric point:
9.67
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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