AMACR Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. Belongs to the CaiB/BaiF CoA-transferase family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC; Isomerase; Lipid Metabolism - primary bile acid biosynthesis; Mitochondrial
Chromosomal Location of Human Ortholog: 5p13.2
Cellular Component:  cytoplasm; intracellular membrane-bound organelle; mitochondrion; peroxisomal matrix; peroxisome; plasma membrane
Molecular Function:  alpha-methylacyl-CoA racemase activity; receptor binding
Biological Process:  bile acid biosynthetic process; bile acid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase
Disease: Alpha-methylacyl-coa Racemase Deficiency; Bile Acid Synthesis Defect, Congenital, 4
Reference #:  Q9UHK6 (UniProtKB)
Alt. Names/Synonyms: 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; AMACR; CBAS4; RACE; RM
Gene Symbols: AMACR
Molecular weight: 42,387 Da
Basal Isoelectric point: 6.07  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB