FKBP15
May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase. Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement. Belongs to the FKBP-type PPIase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Unknown function |
Chromosomal Location of mouse Ortholog: 4|4 B3 |
Cellular Component:
actin cytoskeleton; axon; cell projection; cytoplasm; endosome; growth cone; membrane
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Molecular Function:
actin binding; peptidyl-prolyl cis-trans isomerase activity
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Biological Process:
endocytosis
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Reference #:
Q6P9Q6
(UniProtKB)
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Alt. Names/Synonyms: 133 kDa FK506-binding protein; 133 kDa FKBP; BB131447; C430014M02Rik; FK506 binding protein 15; FK506-binding protein 133; FK506-binding protein 15; FKB15; FKBO133; FKBP-133; FKBP-15; FKBP13; Fkbp133; Fkbp15; Kiaa0674; MGC169330; mKIAA0674; WAFL; WASP and FKBP-like
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Gene Symbols: Fkbp15
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Molecular weight:
132,961 Da
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Basal Isoelectric point:
4.98
Predict pI for various phosphorylation states
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