FKBP15 May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase. Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement. Belongs to the FKBP-type PPIase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 4|4 B3
Cellular Component:  axon; cell projection; cytoplasm; endosome; growth cone; membrane
Molecular Function:  actin binding
Biological Process:  endocytosis; negative regulation of phosphatase activity
Reference #:  Q6P9Q6 (UniProtKB)
Alt. Names/Synonyms: 133 kDa FK506-binding protein; 133 kDa FKBP; BB131447; C430014M02Rik; FK506 binding protein 15; FK506-binding protein 133; FK506-binding protein 15; FKB15; FKBO133; FKBP-133; FKBP-15; FKBP13; Fkbp133; Fkbp15; Kiaa0674; MGC169330; mKIAA0674; WAFL; WASP and FKBP-like
Gene Symbols: Fkbp15
Molecular weight: 132,961 Da
Basal Isoelectric point: 4.98  Predict pI for various phosphorylation states
Select Structure to View Below

FKBP15

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene