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K81
Belongs to the intermediate filament family. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 15 F2|15 56.9 cM |
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Cellular Component:
intermediate filament; keratin filament
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Molecular Function:
structural constituent of skin epidermis
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Biological Process:
intermediate filament organization; keratinization
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Reference #:
Q9ERE2
(UniProtKB)
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Alt. Names/Synonyms: AA589625; K81; keratin 81; keratin complex 2, basic, gene 19; Keratin, type II cuticular Hb1; Keratin-81; Krt2-1; Krt2-19; Krt81; Type II hair keratin Hb1
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Gene Symbols: Krt81
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Molecular weight:
52,863 Da
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Basal Isoelectric point:
5.63
Predict pI for various phosphorylation states
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