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CFAP298
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance of cilium motility. Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway. May suppress canonical Wnt signaling activity. Belongs to the CFAP298 family. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of mouse Ortholog: 16|16 C3.3 |
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Cellular Component:
cell projection; cilium; cytoplasm; cytoskeleton; cytosol
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Biological Process:
cilium assembly; regulation of cilium movement
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Reference #:
Q8BL95
(UniProtKB)
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Alt. Names/Synonyms: 1110004E09Rik; C21orf59; CF298; Cfap298; cilia and flagella associate protien 298; Cilia- and flagella-associated protein 298; CU059; hypothetical protein LOC68001; OTTMUSP00000021472; Protein kurly homolog; RIKEN cDNA 1110004E09 gene; UPF0769 protein C21orf59 homolog
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Gene Symbols: Cfap298
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Molecular weight:
33,190 Da
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Basal Isoelectric point:
6.23
Predict pI for various phosphorylation states
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