C21orf59 Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance of cilium motility. Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway. May suppress canonical Wnt signaling activity. Belongs to the CFAP298 family. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 16|16 C3.3
Cellular Component:  cell projection; cilium; cytoplasm; cytoskeleton; cytosol
Biological Process:  cilium assembly; regulation of cilium movement
Reference #:  Q8BL95 (UniProtKB)
Alt. Names/Synonyms: 1110004E09Rik; CU059; hypothetical protein LOC68001; OTTMUSP00000021472; RIKEN cDNA 1110004E09 gene; UPF0769 protein C21orf59 homolog
Gene Symbols: 1110004E09Rik
Molecular weight: 33,190 Da
Basal Isoelectric point: 6.23  Predict pI for various phosphorylation states
Select Structure to View Below

C21orf59

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein