ANKZF1 Plays a role in the cellular response to hydrogen peroxide and in the maintenance of mitochondrial integrity under conditions of cellular stress. Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Belongs to the ANKZF1/VMS1 family. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of mouse Ortholog: 1 C4|1 38.62 cM
Cellular Component:  Cdc48p-Npl4p-Vms1p AAA ATPase complex; cytoplasm
Molecular Function:  metal ion binding; nucleic acid binding; protein binding
Biological Process:  cellular response to hydrogen peroxide; mitochondria-associated ubiquitin-dependent protein catabolic process; nuclear protein quality control by the ubiquitin-proteasome system; ubiquitin-dependent ERAD pathway
Reference #:  Q80UU1 (UniProtKB)
Alt. Names/Synonyms: 1300008P06Rik; 2810025E10Rik; ankyrin repeat and zinc finger domain containing 1; ankyrin repeat and zinc finger domain containing protein; Ankyrin repeat and zinc finger domain-containing protein 1; ANKZ1; Ankzf1; D1Ertd161; D1Ertd161e; VMS1
Gene Symbols: Ankzf1
Molecular weight: 82,976 Da
Basal Isoelectric point: 8.61  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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ANKZF1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene