HSPC148 Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Belongs to the CWC15 family. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; Spliceosome
Chromosomal Location of mouse Ortholog: 9|9 A2
Cellular Component:  catalytic step 2 spliceosome; mitochondrion; nuclear speck; nucleus; spliceosomal complex; U2-type catalytic step 2 spliceosome
Molecular Function:  RNA binding
Biological Process:  mRNA cis splicing, via spliceosome; mRNA processing; mRNA splicing, via spliceosome; RNA splicing
Reference #:  Q9JHS9 (UniProtKB)
Alt. Names/Synonyms: 0610040D20Rik; 2900052N06Rik; c11orf5; Cwc15; CWC15 homolog; CWC15 homolog (S. cerevisiae); CWC15 spliceosome-associated protein; Ed1; Embryonic development factor 1; HSPC148; mED1; nucleoporin; Protein CWC15 homolog; Spliceosome-associated protein CWC15 homolog
Gene Symbols: Cwc15
Molecular weight: 26,624 Da
Basal Isoelectric point: 5.54  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene