SSTK
Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Highly expressed in testis. Expressed at lower levels in colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes. Note: This description may include information from UniProtKB.
|
Protein type: CAMK group; Cancer Testis Antigen (CTA); EC 2.7.11.1; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); TSSK family |
Chromosomal Location of mouse Ortholog: 8|8 B3.3 |
Cellular Component:
nucleotide-activated protein kinase complex
|
Molecular Function:
ATP binding; kinase activity; magnesium ion binding; metal ion binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; protein-containing complex binding; transferase activity
|
Biological Process:
cell differentiation; cellular response to glucose starvation; intracellular signal transduction; multicellular organism development; negative regulation of TOR signaling; peptidyl-serine phosphorylation; phosphorylation; protein phosphorylation; sperm DNA condensation; spermatogenesis
|
Reference #:
Q925K9
(UniProtKB)
|
Alt. Names/Synonyms: CT72; serine/threonine protein kinase SSTK; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; Sstk; Testis-specific kinase 6; testis-specific serine kinase 6; Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK-6; Tssk6
|
Gene Symbols: Tssk6
|
Molecular weight:
30,287 Da
|
Basal Isoelectric point:
9.3
Predict pI for various phosphorylation states
|