MAGE-D2 Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule. Widely expressed. In the developing and adult kidney, expressed in the thick ascending limb of the loop of Henle and the distal convoluted tubules outside the loop. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of mouse Ortholog: X|X F3
Cellular Component:  cytosol; nucleolus; nucleus
Biological Process:  female pregnancy; renal sodium ion absorption
Reference #:  Q9ER67 (UniProtKB)
Alt. Names/Synonyms: 4833439A22Rik; MAGE family member D2; Mage-d; Mage-d2; Maged2; Maged2 protein; melanoma antigen family D, 2; Melanoma antigen, family D, 2; melanoma-associated antigen D2; ORF1; OTTMUSP00000020716; OTTMUSP00000020722
Gene Symbols: Maged2
Molecular weight: 65,400 Da
Basal Isoelectric point: 9.19  Predict pI for various phosphorylation states
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MAGE-D2

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene