EEF1AKMT4-ECE2 Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity. May play a role in amyloid-beta processing. In the C-terminal section; belongs to the peptidase M13 family. 1 alternatively spliced human isoform has been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of mouse Ortholog: 16|16 B1
Cellular Component:  cytoplasmic vesicle membrane
Molecular Function:  metalloendopeptidase activity
Reference #:  P0DPD9 (UniProtKB)
Alt. Names/Synonyms: EEF1A lysine methyltransferase 4; Eef1akmt4; Eef1akmt4-Ece2; Eef1akmt4-Ece2 readthrough; EEF1AKMT4-ECE2 readthrough transcript protein; EFCE2; Endothelin-converting enzyme 2 region; Methyltransferase-like region
Gene Symbols: Eef1akmt4-Ece2
Molecular weight: 99,480 Da
Basal Isoelectric point: 4.96  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein