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SPATA6
Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits. Belongs to the SPATA6 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Secreted; Secreted, signal peptide |
| Chromosomal Location of mouse Ortholog: 4|4 D1 |
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Cellular Component:
cell projection; cilium; extracellular region; motile cilium; sperm connecting piece
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Molecular Function:
myosin light chain binding
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Biological Process:
cell differentiation; motile cilium assembly; multicellular organism development; spermatogenesis
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Reference #:
Q3U6K5
(UniProtKB)
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Alt. Names/Synonyms: 1700062C23Rik; AI790763; Hash; Kinesin-related protein; KRP; Mash; OTTMUSP00000009870; SPAT6; Spata6; spermatogenesis associated 6; Spermatogenesis-associated protein 6
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Gene Symbols: Spata6
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Molecular weight:
56,101 Da
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Basal Isoelectric point:
8.8
Predict pI for various phosphorylation states
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