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JADE3
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Belongs to the JADE family. Ubiquitously expressed, with highest levels in placenta and uterus. Note: This description may include information from UniProtKB.
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| Protein type: Transcription factor |
| Chromosomal Location of mouse Ortholog: X|X A1.3 |
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Cellular Component:
histone acetyltransferase complex; nucleoplasm
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Molecular Function:
metal ion binding
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Biological Process:
histone H4-K12 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; histone modification; regulation of cell cycle; regulation of DNA biosynthetic process; regulation of DNA replication; regulation of transcription by RNA polymerase II
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Reference #:
Q6IE82
(UniProtKB)
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Alt. Names/Synonyms: 5730598B06; AI851988; AW544806; jade family PHD finger 3; Jade family PHD finger protein 3; Jade3; Kiaa0215; mKIAA0215; PHD finger protein 16; Phf1; Phf16; Protein Jade-3
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Gene Symbols: Jade3
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Molecular weight:
93,455 Da
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Basal Isoelectric point:
6.6
Predict pI for various phosphorylation states
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