peregrin Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation. Positively regulates the transcription of RUNX1 and RUNX2. High levels in testis. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 6|6 E3
Cellular Component:  cytoplasm; cytosol; MOZ/MORF histone acetyltransferase complex; nucleus; plasma membrane
Molecular Function:  DNA binding; metal ion binding; nucleic acid binding
Biological Process:  chromatin organization; common myeloid progenitor cell proliferation; histone H3 acetylation; histone H3-K23 acetylation; neural tube formation; positive regulation of transcription, DNA-templated; regulation of fibroblast proliferation; vasculogenesis
Reference #:  B2RRD7 (UniProtKB)
Alt. Names/Synonyms: 4833438B11Rik; 4930540D11Rik; bromodomain and PHD finger containing, 1; Bromodomain and PHD finger-containing protein 1; bromodomain containing 1; Brpf1; Brpf2; OTTMUSP00000026060; Peregrin
Gene Symbols: Brpf1
Molecular weight: 137,310 Da
Basal Isoelectric point: 8.16  Predict pI for various phosphorylation states
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peregrin

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein