PRAM1 May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P. Expressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 17|17 B1
Cellular Component:  plasma membrane; protein-containing complex
Molecular Function:  lipid binding; protein kinase binding
Biological Process:  integrin-mediated signaling pathway; protein localization to plasma membrane; regulation of neutrophil degranulation; T cell receptor signaling pathway
Reference #:  Q6BCL1 (UniProtKB)
Alt. Names/Synonyms: AY665714; PML-RAR alpha-regulated adaptor molecule 1; PML-RARA-regulated adapter molecule 1; PRAM; PRAM-1; Pram1
Gene Symbols: Pram1
Molecular weight: 75,508 Da
Basal Isoelectric point: 9.65  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene