F25965 Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 7|7 B1
Cellular Component:  transcriptional repressor complex
Reference #:  Q9D8N6 (UniProtKB)
Alt. Names/Synonyms: 1810054G18Rik; Antolefinin; Antolefinine; F25965; lin-37 homolog (C. elegans); Lin37; OTTMUSP00000032214; Protein lin-37 homolog
Gene Symbols: Lin37
Molecular weight: 28,378 Da
Basal Isoelectric point: 9.14  Predict pI for various phosphorylation states
Select Structure to View Below

F25965

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene