liprin alpha 1 May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. Belongs to the liprin family. Liprin-alpha subfamily. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7|7 F5
Cellular Component:  axon; cytosol; dendrite; focal adhesion; protein-containing complex
Molecular Function:  protein binding
Biological Process:  negative regulation of protein localization to plasma membrane; negative regulation of stress fiber assembly
Reference #:  B2RXW8 (UniProtKB)
Alt. Names/Synonyms: C030014K08Rik; C87158; LIP.1; LIP1; liprin; MGC189815; MGC189929; Ppfia1; Ppfia1 protein; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein, alpha 1
Gene Symbols: Ppfia1
Molecular weight: 140,135 Da
Basal Isoelectric point: 5.8  Predict pI for various phosphorylation states
Select Structure to View Below

liprin alpha 1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein