ZC3H14 Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides. Belongs to the ZC3H14 family. Isoform 1 and isoform 6 are expressed in fetal and adult brain. Isoform 1 and isoform 6 are expressed in fetal and adult temporal lobe. 10 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; RNA-binding
Chromosomal Location of mouse Ortholog: 12|12 E
Cellular Component:  axon cytoplasm; cytoplasm; dendrite cytoplasm; nuclear speck; nucleolus; nucleus; ribonucleoprotein complex
Molecular Function:  metal ion binding; poly(A) binding; RNA binding
Biological Process:  negative regulation of mRNA polyadenylation; regulation of mRNA stability
Reference #:  Q8BJ05 (UniProtKB)
Alt. Names/Synonyms: 1010001P15Rik; 1700016A15Rik; 2700069A02Rik; AU014748; Zc3h14; ZC3HE; Zinc finger CCCH domain-containing protein 14; zinc finger CCCH type containing 14; zinc finger CCCH-type containing 14
Gene Symbols: Zc3h14
Molecular weight: 82,409 Da
Basal Isoelectric point: 7.04  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene