MLKL Belongs to the protein kinase superfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; TKL group; TKL-Unique family
Chromosomal Location of Human Ortholog: 8|8 E1
Cellular Component:  cytoplasm; membrane; plasma membrane
Molecular Function:  ATP binding; identical protein binding; JUN kinase kinase kinase activity; nucleotide binding; protein binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity
Biological Process:  activation of JNK activity; cell surface receptor signaling pathway; MAPK cascade; necroptotic process; programmed cell death; protein amino acid phosphorylation
Reference #:  Q9D2Y4 (UniProtKB)
Alt. Names/Synonyms: 9130019I15Rik; mixed lineage kinase domain-like; Mixed lineage kinase domain-like protein; Mlkl
Gene Symbols: Mlkl
Molecular weight: 54,317 Da
Basal Isoelectric point: 8.5  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

MLKL

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene