EHBP1 May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking. Required for perinuclear sorting and insulin-regulated recycling of SLC2A4/GLUT4 in adipocytes. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of mouse Ortholog: 11 A3.2|11 14.1 cM
Cellular Component:  cytoplasm; cytosol; endosome; filamentous actin; membrane; microtubule organizing center; nucleoplasm; plasma membrane
Molecular Function:  protein binding
Biological Process:  actin cytoskeleton organization; endocytosis; protein transport
Reference #:  Q69ZW3 (UniProtKB)
Alt. Names/Synonyms: AF424697; DNA sequence AF424697; EH domain binding protein 1; EH domain-binding protein 1; Ehbp1; Flj21950; Kiaa0903; KIAA0903-like; NACSIN; OTTMUSP00000005431
Gene Symbols: Ehbp1
Molecular weight: 139,104 Da
Basal Isoelectric point: 5.27  Predict pI for various phosphorylation states
CST Pathways:  Insulin Receptor Signaling
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene