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EHBP1
May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking. Required for perinuclear sorting and insulin-regulated recycling of SLC2A4/GLUT4 in adipocytes. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Vesicle |
| Chromosomal Location of mouse Ortholog: 11 A3.2|11 14.1 cM |
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Cellular Component:
cytoplasm; cytosol; endosome; filamentous actin; membrane; microtubule organizing center; nucleoplasm; plasma membrane
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Molecular Function:
protein binding
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Biological Process:
actin cytoskeleton organization; endocytosis; protein transport
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Reference #:
Q69ZW3
(UniProtKB)
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Alt. Names/Synonyms: AF424697; DNA sequence AF424697; EH domain binding protein 1; EH domain-binding protein 1; Ehbp1; Flj21950; Kiaa0903; KIAA0903-like; NACSIN; OTTMUSP00000005431
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Gene Symbols: Ehbp1
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Molecular weight:
139,104 Da
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Basal Isoelectric point:
5.27
Predict pI for various phosphorylation states
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CST Pathways:
Insulin Receptor Signaling
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