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BICC1
Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development. Belongs to the BicC family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding |
| Chromosomal Location of mouse Ortholog: 10 B5.3|10 36.75 cM |
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Cellular Component:
cytoplasm
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Molecular Function:
nucleic acid binding; protein binding; RNA binding
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Biological Process:
determination of left/right symmetry; heart development; kidney development; multicellular organism development; negative regulation of canonical Wnt signaling pathway
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Reference #:
Q99MQ1
(UniProtKB)
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Alt. Names/Synonyms: Bic-; Bic-C; bicaudal C homolog 1; bicaudal C homolog 1 (Drosophila); BicC family RNA binding protein 1; Bicc1; bpk; jcp; jcpk; juvenile congenital polycystic kidney disease; MGC124370; OTTMUSP00000029836; polycystic kidney mutation of BALB/c origin; Protein bicaudal C homolog 1
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Gene Symbols: Bicc1
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Molecular weight:
105,037 Da
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Basal Isoelectric point:
8.79
Predict pI for various phosphorylation states
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